Concomitant administration of anti-tuberculosis medication and antidiabetic drugs; a drug-drug interaction study

Abstract

Diabetes mellitus is a common medical problem seen in around the world. There is a chance that diabetes might co-occur with other medical diseases. The concomitant occurrence between diabetes and tuberculosis is possible and needs good clinical management. Here, the authors use a standard bioinformatics study to assess and predict drug-drug interaction due to concomitant administration of anti-tuberculosis and anti-diabetic drugs. According to the study, there is no serious drug-drug interaction from concomitant use of anti-tuberculosis and anti-diabetic drugs. Nevertheless, there are several possible non-severe interactions that lead to the necessity for a practitioner to carefully monitor the concomitant use of anti-tuberculosis and anti-diabetic drugs.